Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception

Nonhormonal products for on-demand contraception are a global health technology gap; this unmet need motivated us to pursue the use of sperm-binding monoclonal antibodies to enable effective on-demand contraception. Here, using the cGMP-compliant Nicotiana-expression system, we produced an ultrapote...

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Detalles Bibliográficos
Autores principales: Shrestha, Bhawana, Vincent, Kathleen, Schaefer, Alison, Zhu, Yong, Vargas, Gracie, Motamedi, Massoud, Swope, Kelsi, Morton, Josh, Simpson, Carrie, Pham, Henry, Brennan, Miles B., Pauly, Michael H., Zeitlin, Larry, Bratcher, Barry, Whaley, Kevin J., Moench, Thomas R., Lai, Samuel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640842/
https://www.ncbi.nlm.nih.gov/pubmed/34815336
http://dx.doi.org/10.1073/pnas.2107832118

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