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miR-155 regulates pro- and anti-inflammatory cytokine expression in human monocytes during chronic hepatitis C virus infection

BACKGROUND: Hepatitis C virus (HCV) dysregulates innate and adaptive immune responses while monocytes (M) play a crucial role in linking innate and adaptive immunity to control viral infection. A transcription factor T-bet is upregulated to dampen M functions via the c-Jun N-terminal kinase (JNK) pa...

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Detalles Bibliográficos
Autores principales: Zhou, Yun, Zhang, Peixin, Zheng, Xuyang, Ye, Chuantao, Li, Mengyuan, Bian, Peiyu, Fan, Chao, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640902/
https://www.ncbi.nlm.nih.gov/pubmed/34926662
http://dx.doi.org/10.21037/atm-21-2620