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The molecular evolution of function in the CFTR chloride channel

The ATP-binding cassette (ABC) transporter superfamily includes many proteins of clinical relevance, with genes expressed in all domains of life. Although most members use the energy of ATP binding and hydrolysis to accomplish the active import or export of various substrates across membranes, the c...

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Detalles Bibliográficos
Autores principales:	Infield, Daniel T., Strickland, Kerry M., Gaggar, Amit, McCarty, Nael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640958/ https://www.ncbi.nlm.nih.gov/pubmed/34647973 http://dx.doi.org/10.1085/jgp.202012625

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