Cargando…

MKK7-mediated phosphorylation of JNKs regulates the proliferation and apoptosis of human spermatogonial stem cells

BACKGROUND: Human spermatogonial stem cells (SSCs) are the basis of spermatogenesis. However, little is known about the developmental regulatory mechanisms of SSC due to sample origin and species differences. AIM: To investigates the mechanisms involved in the proliferation of human SSC. METHODS: Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Zeng-Hui, Huang, Chuan, Ji, Xi-Ren, Zhou, Wen-Jun, Luo, Xue-Feng, Liu, Qian, Tang, Yu-Lin, Gong, Fei, Zhu, Wen-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641020/ https://www.ncbi.nlm.nih.gov/pubmed/34909124 http://dx.doi.org/10.4252/wjsc.v13.i11.1797

Ejemplares similares

SPOC domain-containing protein 1 regulates the proliferation and apoptosis of human spermatogonial stem cells through adenylate kinase 4
por: Zhou, Dai, et al.
Publicado: (2022)

JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21
por: Colleoni, B, et al.
Publicado: (2017)

Activation of JNKs is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells
por: Zhao, Yan-fang, et al.
Publicado: (2013)

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells
por: Bae, Ki Beom, et al.
Publicado: (2017)

PDRPS7 protects cardiac cells from hypoxia/reoxygenation injury through inactivation of JNKs
por: Duan, Yulian, et al.
Publicado: (2020)

Assessing developmental roles of MKK4 and MKK7 in vitro
por: Wang, Jingcai, et al.
Publicado: (2012)

TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL
por: Zhou, Dai, et al.
Publicado: (2021)

JNKs protect from cholestatic liver disease progression by modulating Apelin signalling
por: Mohamed, Mohamed Ramadan, et al.
Publicado: (2023)

Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients
por: Wang, Pu-Ning, et al.
Publicado: (2017)

Neuroprotection by MKK7 inhibition in excitotoxicity
por: Vercelli, Alessandro, et al.
Publicado: (2015)

c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury
por: Shvedova, Maria, et al.
Publicado: (2018)

Role of c-Jun N-Terminal Kinases (JNKs) in Epilepsy and Metabolic Cognitive Impairment
por: Busquets, Oriol, et al.
Publicado: (2019)

Spermatogonial stem cells as a therapeutic alternative for fertility preservation of prepubertal boys
por: Galuppo, Andrea Giannotti
Publicado: (2015)

Crystal structure of the phosphorylated Arabidopsis MKK5 reveals activation mechanism of MAPK kinases : Activation mechanism of AtMKK5
por: Pei, Chao-Jun, et al.
Publicado: (2022)

Yangzheng Sanjie decoction regulates proliferation and apoptosis of gastric cancer cells by enhancing let-7a expression
por: Deng, Hai-Xia, et al.
Publicado: (2017)

TSPY1 suppresses USP7-mediated p53 function and promotes spermatogonial proliferation
por: Shen, Ying, et al.
Publicado: (2018)

MAGEB2-Mediated Degradation of EGR1 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cell Lines
por: Zhao, Xueheng, et al.
Publicado: (2023)

MSK1 promotes cell proliferation and metastasis in uveal melanoma by phosphorylating CREB
por: Li, Jianchang, et al.
Publicado: (2019)

Functions of the AP-2α gene in activating apoptosis and inhibiting proliferation of gastric cancer cells both in vitro and in vivo
por: Zeng, Changqing, et al.
Publicado: (2017)

Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress
por: Hou, Xiao-Xue, et al.
Publicado: (2023)

Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death
por: Syc-Mazurek, Stephanie B., et al.
Publicado: (2018)

Glycylglycine plays critical roles in the proliferation of spermatogonial stem cells
por: Xu, Bo, et al.
Publicado: (2019)

Offspring production of ovarian organoids derived from spermatogonial stem cells by defined factors with chromatin reorganization
por: Luo, Huacheng, et al.
Publicado: (2021)

Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions
por: Bi, Yang-Hui, et al.
Publicado: (2019)

Combined (15)N-Labeling and TandemMOAC Quantifies Phosphorylation of MAP Kinase Substrates Downstream of MKK7 in Arabidopsis
por: Huck, Nicola V., et al.
Publicado: (2017)

Activation of the JNKs/ATM-p53 axis is indispensable for the cytoprotection of dermal fibroblasts exposed to UVB radiation
por: Mavrogonatou, Eleni, et al.
Publicado: (2022)

Probing the interaction interface of the GADD45β/MKK7 and MKK7/DTP3 complexes by chemical cross-linking mass spectrometry
por: Rega, Camilla, et al.
Publicado: (2018)

A Non-Redundant Role for Drosophila Mkk4 and Hemipterous/Mkk7 in TAK1-Mediated Activation of JNK
por: Geuking, Peter, et al.
Publicado: (2009)

Dual Mkk4 and Mkk7 Gene Deletion in Adult Mouse Causes an Impairment of Hippocampal Immature Granule Cells
por: Castro-Torres, Rubén Darío, et al.
Publicado: (2021)

Meclofenamic acid represses spermatogonial proliferation through modulating m(6)A RNA modification
por: Huang, Tao, et al.
Publicado: (2019)

Isolation and Proliferation of Spermatogonial Cells from Ghezel Sheep
por: Qasemi-Panahi, Babak, et al.
Publicado: (2018)

Mechanistic target of rapamycin kinase (Mtor) is required for spermatogonial proliferation and differentiation in mice
por: Cao, Jun, et al.
Publicado: (2019)

Acetyl-11-keto-β-boswellic acid inhibits proliferation and induces apoptosis of gastric cancer cells through the phosphatase and tensin homolog /Akt/ cyclooxygenase-2 signaling pathway
por: Sun, Meng-Xue, et al.
Publicado: (2020)

Author Correction: Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death
por: Syc-Mazurek, Stephanie B., et al.
Publicado: (2019)

TBL1XR1 induces cell proliferation and inhibit cell apoptosis by the PI3K/AKT pathway in pancreatic ductal adenocarcinoma
por: Gu, Jian-Feng, et al.
Publicado: (2020)

AB182. Efficient generation of haploid spermatids with Fertilization and development capacity from human spermatogonial stem cells of cryptorchid patients
por: Yang, Shi, et al.
Publicado: (2014)

Tomato SlMKK2 and SlMKK4 contribute to disease resistance against Botrytis cinerea
por: Li, Xiaohui, et al.
Publicado: (2014)

Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium
por: TANG, BO, et al.
Publicado: (2011)

Defective anchoring of JNK1 in the cytoplasm by MKK7 in Jurkat cells is associated with resistance to Fas-mediated apoptosis
por: Wang, Jing, et al.
Publicado: (2011)

Inhibition of HDAC4 Attenuated JNK/c-Jun-Dependent Neuronal Apoptosis and Early Brain Injury Following Subarachnoid Hemorrhage by Transcriptionally Suppressing MKK7
por: Wu, Liqiang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mfkr28n7bnu52vq31ni8ajpcsv