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Repeated injury promotes tracheobronchial tissue stem cell attrition

Chronic lung disease has been attributed to stem cell aging and/or exhaustion. We investigated these mechanisms using mouse and human tracheobronchial tissue‐specific stem cells (TSC). In mouse, chromatin labeling and flow cytometry demonstrated that naphthalene (NA) injury activated a subset of TSC...

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Detalles Bibliográficos
Autores principales: Ghosh, Moumita, Hill, Cynthia L., Alsudayri, Alfahdah, Lallier, Scott W., Hayes, Don, Wijeratne, Saranga, Tan, Zhang Hong, Chiang, Tendy, Mahoney, John E., Carraro, Gianni, Stripp, Barry R., Reynolds, Susan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641087/
https://www.ncbi.nlm.nih.gov/pubmed/34546001
http://dx.doi.org/10.1002/sctm.21-0032