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The heterogeneity of megakaryocytes and platelets and implications for ex vivo platelet generation

Platelets, the chief effector of hemostasis, are small anucleate blood cells generated from megakaryocytes (MKs), and the defects in platelet production or function lead to a variety of bleeding complications. Emerging evidence indicates that MKs and platelets are much more diverse than previously a...

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Detalles Bibliográficos
Autores principales: Liu, Cuicui, Huang, Baiming, Wang, Hongtao, Zhou, Jiaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641090/
https://www.ncbi.nlm.nih.gov/pubmed/34536061
http://dx.doi.org/10.1002/sctm.21-0264