Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence

BACKGROUND: Endothelial cell senescence is the state of permanent cell cycle arrest and plays a critical role in the pathogenesis of age-related diseases. However, a comprehensive understanding of the gene regulatory network, including genome-wide alternative splicing machinery, involved in endothel...

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Detalles Bibliográficos
Autores principales: Ohori, Momoko, Nakayama, Yusuke, Ogasawara-Shimizu, Mari, Toyoshiba, Hiroyoshi, Nakanishi, Atsushi, Aparicio, Samuel, Araki, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641155/
https://www.ncbi.nlm.nih.gov/pubmed/34856941
http://dx.doi.org/10.1186/s12864-021-08185-x

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