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Identification of transcription factors and construction of a novel miRNA regulatory network in primary osteoarthritis by integrated analysis

BACKGROUNDS: As osteoarthritis (OA) disease-modifying therapies are not available, novel therapeutic targets need to be discovered and prioritized. Here, we aim to identify miRNA signatures in patients to fully elucidate regulatory mechanism of OA pathogenesis and advance in basic understanding of t...

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Detalles Bibliográficos
Autores principales: Jiang, Ying, Shen, Yi, Ding, Liyan, Xia, Shengli, Jiang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641180/
https://www.ncbi.nlm.nih.gov/pubmed/34856957
http://dx.doi.org/10.1186/s12891-021-04894-2

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