Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients

Adaptive immunity is a fundamental component in controlling COVID-19. In this process, follicular helper T (Tfh) cells are a subset of CD4(+) T cells that mediate the production of protective antibodies; however, the SARS-CoV-2 epitopes activating Tfh cells are not well characterized. Here, we ident...

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Detalles Bibliográficos
Autores principales: Lu, Xiuyuan, Hosono, Yuki, Nagae, Masamichi, Ishizuka, Shigenari, Ishikawa, Eri, Motooka, Daisuke, Ozaki, Yuki, Sax, Nicolas, Maeda, Yuichi, Kato, Yasuhiro, Morita, Takayoshi, Shinnakasu, Ryo, Inoue, Takeshi, Onodera, Taishi, Matsumura, Takayuki, Shinkai, Masaharu, Sato, Takashi, Nakamura, Shota, Mori, Shunsuke, Kanda, Teru, Nakayama, Emi E., Shioda, Tatsuo, Kurosaki, Tomohiro, Takeda, Kiyoshi, Kumanogoh, Atsushi, Arase, Hisashi, Nakagami, Hironori, Yamashita, Kazuo, Takahashi, Yoshimasa, Yamasaki, Sho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641254/
https://www.ncbi.nlm.nih.gov/pubmed/34647971
http://dx.doi.org/10.1084/jem.20211327

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