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Investigation of prediction accuracy and the impact of sample size, ancestry, and tissue in transcriptome‐wide association studies
In transcriptome‐wide association studies (TWAS), gene expression values are predicted using genotype data and tested for association with a phenotype. The power of this approach to detect associations relies, at least in part, on the accuracy of the prediction. Here we compare the prediction accura...
Autores principales: | Fryett, James J., Morris, Andrew P., Cordell, Heather J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641384/ https://www.ncbi.nlm.nih.gov/pubmed/32190932 http://dx.doi.org/10.1002/gepi.22290 |
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