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Investigation of prediction accuracy and the impact of sample size, ancestry, and tissue in transcriptome‐wide association studies

In transcriptome‐wide association studies (TWAS), gene expression values are predicted using genotype data and tested for association with a phenotype. The power of this approach to detect associations relies, at least in part, on the accuracy of the prediction. Here we compare the prediction accura...

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Detalles Bibliográficos
Autores principales: Fryett, James J., Morris, Andrew P., Cordell, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641384/
https://www.ncbi.nlm.nih.gov/pubmed/32190932
http://dx.doi.org/10.1002/gepi.22290

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