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Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19

Coagulopathy in severe COVID-19 is common but poorly understood. The purpose of this study was to determine how SARS-CoV-2 infection impacts histone levels, fibrin structure, and endogenous thrombin potential in the presence and absence of endothelial cells. We studied individuals with SARS-CoV-2 in...

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Detalles Bibliográficos
Autores principales:	Bouchard, Beth A., Colovos, Christos, Lawson, Michael A., Osborn, Zachary T., Sackheim, Adrian M., Mould, Kara J., Janssen, William J., Cohen, Mitchell J., Majumdar, Devdoot, Freeman, Kalev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641427/ https://www.ncbi.nlm.nih.gov/pubmed/34871770 http://dx.doi.org/10.1016/j.vph.2021.106950

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