Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study

INTRODUCTION: The clitoris is partially responsible for sexual arousal. The integrity of the extracellular matrix is essential for clitoral erection. Sexual dysfunction is a phenomenon associated with age. METHODS: The clitoris of cadavers of 20- to 80-year-old women was excised and histologically p...

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Detalles Bibliográficos
Autores principales: Pires, Lucas Alves Sarmento, Babinski, Monique Silva Dias, Junior, Albino Fonseca, Manaia, Jorge Henrique Martins, Babinski, Marcio Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641520/
https://www.ncbi.nlm.nih.gov/pubmed/34900065
http://dx.doi.org/10.5114/aoms/143150
Descripción
Sumario:INTRODUCTION: The clitoris is partially responsible for sexual arousal. The integrity of the extracellular matrix is essential for clitoral erection. Sexual dysfunction is a phenomenon associated with age. METHODS: The clitoris of cadavers of 20- to 80-year-old women was excised and histologically processed. Stereological analysis was performed to quantify the volumetric density of collagen, elastic fibers, and smooth muscle. RESULTS: A significant increase in collagen and a decrease in smooth muscle and elastic fibers were observed in older women. CONCLUSIONS: In short, these changes caused by aging could contribute to female sexual dysfunction concerning clitoral orgasm.

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