Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study

INTRODUCTION: The clitoris is partially responsible for sexual arousal. The integrity of the extracellular matrix is essential for clitoral erection. Sexual dysfunction is a phenomenon associated with age. METHODS: The clitoris of cadavers of 20- to 80-year-old women was excised and histologically p...

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Detalles Bibliográficos
Autores principales: Pires, Lucas Alves Sarmento, Babinski, Monique Silva Dias, Junior, Albino Fonseca, Manaia, Jorge Henrique Martins, Babinski, Marcio Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641520/
https://www.ncbi.nlm.nih.gov/pubmed/34900065
http://dx.doi.org/10.5114/aoms/143150
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author Pires, Lucas Alves Sarmento
Babinski, Monique Silva Dias
Junior, Albino Fonseca
Manaia, Jorge Henrique Martins
Babinski, Marcio Antonio
author_facet Pires, Lucas Alves Sarmento
Babinski, Monique Silva Dias
Junior, Albino Fonseca
Manaia, Jorge Henrique Martins
Babinski, Marcio Antonio
author_sort Pires, Lucas Alves Sarmento
collection PubMed
description INTRODUCTION: The clitoris is partially responsible for sexual arousal. The integrity of the extracellular matrix is essential for clitoral erection. Sexual dysfunction is a phenomenon associated with age. METHODS: The clitoris of cadavers of 20- to 80-year-old women was excised and histologically processed. Stereological analysis was performed to quantify the volumetric density of collagen, elastic fibers, and smooth muscle. RESULTS: A significant increase in collagen and a decrease in smooth muscle and elastic fibers were observed in older women. CONCLUSIONS: In short, these changes caused by aging could contribute to female sexual dysfunction concerning clitoral orgasm.
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spelling pubmed-86415202021-12-09 Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study Pires, Lucas Alves Sarmento Babinski, Monique Silva Dias Junior, Albino Fonseca Manaia, Jorge Henrique Martins Babinski, Marcio Antonio Arch Med Sci Research Letter INTRODUCTION: The clitoris is partially responsible for sexual arousal. The integrity of the extracellular matrix is essential for clitoral erection. Sexual dysfunction is a phenomenon associated with age. METHODS: The clitoris of cadavers of 20- to 80-year-old women was excised and histologically processed. Stereological analysis was performed to quantify the volumetric density of collagen, elastic fibers, and smooth muscle. RESULTS: A significant increase in collagen and a decrease in smooth muscle and elastic fibers were observed in older women. CONCLUSIONS: In short, these changes caused by aging could contribute to female sexual dysfunction concerning clitoral orgasm. Termedia Publishing House 2021-10-29 /pmc/articles/PMC8641520/ /pubmed/34900065 http://dx.doi.org/10.5114/aoms/143150 Text en Copyright: © 2021 Termedia & Banach https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Research Letter
Pires, Lucas Alves Sarmento
Babinski, Monique Silva Dias
Junior, Albino Fonseca
Manaia, Jorge Henrique Martins
Babinski, Marcio Antonio
Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
title Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
title_full Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
title_fullStr Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
title_full_unstemmed Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
title_short Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
title_sort changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641520/
https://www.ncbi.nlm.nih.gov/pubmed/34900065
http://dx.doi.org/10.5114/aoms/143150
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