Triggering Receptor Expressed on Myeloid Cells 2 Protects Dopaminergic Neurons by Promoting Autophagy in the Inflammatory Pathogenesis of Parkinson’s Disease

Parkinson’s disease is a neurodegenerative disorder with an inflammatory response as the core pathogenic mechanism. Previous human genetics findings support the view that the loss of TREM2 function will aggravate neurodegeneration, and TREM2 is one of the most highly expressed receptors in microglia...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Wei, Lv, Qiankun, Xiao, Yunfei, Zhong, Zhen, Hu, Binbin, Yan, Si, Yan, Yufang, Zhang, Junjun, Shi, Ting, Jiang, Lijuan, Li, Wen, Lu, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641649/
https://www.ncbi.nlm.nih.gov/pubmed/34867158
http://dx.doi.org/10.3389/fnins.2021.745815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641649/
https://www.ncbi.nlm.nih.gov/pubmed/34867158
http://dx.doi.org/10.3389/fnins.2021.745815

Ejemplares similares