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Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats
CONTEXT: Danggui Buxue Tang (DBT), one of the popular Danggui (DG) decoctions, has traditionally been used to nourish ‘qi’ (vital energy) and enrich ‘blood’ (body circulation). DBT may possess performance-enhancing effects. OBJECTIVE: This work determines whether DBT can improve physical capacity an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641674/ https://www.ncbi.nlm.nih.gov/pubmed/32538243 http://dx.doi.org/10.1080/13880209.2020.1774622 |
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author | Chang, William Chih-Wei Yen, Ching-Chi Cheng, Chao-Pei Wu, Yu-Tse Hsu, Mei-Chich |
author_facet | Chang, William Chih-Wei Yen, Ching-Chi Cheng, Chao-Pei Wu, Yu-Tse Hsu, Mei-Chich |
author_sort | Chang, William Chih-Wei |
collection | PubMed |
description | CONTEXT: Danggui Buxue Tang (DBT), one of the popular Danggui (DG) decoctions, has traditionally been used to nourish ‘qi’ (vital energy) and enrich ‘blood’ (body circulation). DBT may possess performance-enhancing effects. OBJECTIVE: This work determines whether DBT can improve physical capacity and alter energy expenditure under exercise training. MATERIALS AND METHODS: Forty male Wistar rats were assigned to four groups: sedentary (SE), exercise training (ET), ET supplemented with 0.3 g/kg rat/d DG extract, and ET supplemented with 1.8 g/kg rat/d DBT extract. The supplementations were administered via oral gavage. During the 21-day treatment period, the exercised groups were subjected to a protocol of swimming training with a gradually increased load. Physical performance evaluation was assessed using the forelimb grip strength test and an exhaustive swimming test. Muscle glycogen contents and exercise-related biochemical parameters were analysed. RESULTS: Both herbal supplementations remarkably increased the grip strength (DG by 49.7% and DBT by 85.7%) and prolonged the swimming time (DG by 48.4% and DBT by 72.7%) compared with SE. DBT spared a certain amount of glycogen in the muscle cells under exercise training. Regarding the regulation of fuel usage, DBT had a positive impact alongside ET on promoting aerobic glycolysis via significantly decreasing serum lactate by 31.6% and lactic dehydrogenase levels by 61.8%. CONCLUSIONS: This study found that DBT could be considered a promising sports ergogenic aid for athletic population or fitness enthusiasts. Future work focussing on isolating the bioactive components that truly provide the ergogenic effects would be of interest. |
format | Online Article Text |
id | pubmed-8641674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-86416742021-12-04 Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats Chang, William Chih-Wei Yen, Ching-Chi Cheng, Chao-Pei Wu, Yu-Tse Hsu, Mei-Chich Pharm Biol Research Article CONTEXT: Danggui Buxue Tang (DBT), one of the popular Danggui (DG) decoctions, has traditionally been used to nourish ‘qi’ (vital energy) and enrich ‘blood’ (body circulation). DBT may possess performance-enhancing effects. OBJECTIVE: This work determines whether DBT can improve physical capacity and alter energy expenditure under exercise training. MATERIALS AND METHODS: Forty male Wistar rats were assigned to four groups: sedentary (SE), exercise training (ET), ET supplemented with 0.3 g/kg rat/d DG extract, and ET supplemented with 1.8 g/kg rat/d DBT extract. The supplementations were administered via oral gavage. During the 21-day treatment period, the exercised groups were subjected to a protocol of swimming training with a gradually increased load. Physical performance evaluation was assessed using the forelimb grip strength test and an exhaustive swimming test. Muscle glycogen contents and exercise-related biochemical parameters were analysed. RESULTS: Both herbal supplementations remarkably increased the grip strength (DG by 49.7% and DBT by 85.7%) and prolonged the swimming time (DG by 48.4% and DBT by 72.7%) compared with SE. DBT spared a certain amount of glycogen in the muscle cells under exercise training. Regarding the regulation of fuel usage, DBT had a positive impact alongside ET on promoting aerobic glycolysis via significantly decreasing serum lactate by 31.6% and lactic dehydrogenase levels by 61.8%. CONCLUSIONS: This study found that DBT could be considered a promising sports ergogenic aid for athletic population or fitness enthusiasts. Future work focussing on isolating the bioactive components that truly provide the ergogenic effects would be of interest. Taylor & Francis 2020-06-13 /pmc/articles/PMC8641674/ /pubmed/32538243 http://dx.doi.org/10.1080/13880209.2020.1774622 Text en © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Chang, William Chih-Wei Yen, Ching-Chi Cheng, Chao-Pei Wu, Yu-Tse Hsu, Mei-Chich Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
title | Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
title_full | Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
title_fullStr | Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
title_full_unstemmed | Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
title_short | Chinese herbal decoction (Danggui Buxue Tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
title_sort | chinese herbal decoction (danggui buxue tang) supplementation augments physical performance and facilitates physiological adaptations in swimming rats |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641674/ https://www.ncbi.nlm.nih.gov/pubmed/32538243 http://dx.doi.org/10.1080/13880209.2020.1774622 |
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