2,3,5,4′-Tetrahydroxy-stilbene-2-O-beta-d-glucoside induces autophagy-mediated apoptosis in hepatocytes by upregulating miR-122 and inhibiting the PI3K/Akt/mTOR pathway: implications for its hepatotoxicity

CONTEXT: The potential hepatotoxicity of Polygoni Multiflori Radix (PMR) has attracted much attention, but the specific mechanism of inducing hepatotoxicity is still unclear due to the complexity of its components. OBJECTIVE: This study investigated the specific mechanism by which 2,3,5,4′-tetrahydr...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Xing, Wei, Xiao, Wang-Zhong, Tang, Lin, Wang, Lu, Liu, Meng-Jiao, Dai, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641687/
https://www.ncbi.nlm.nih.gov/pubmed/32881597
http://dx.doi.org/10.1080/13880209.2020.1803367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641687/
https://www.ncbi.nlm.nih.gov/pubmed/32881597
http://dx.doi.org/10.1080/13880209.2020.1803367

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