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SUMO-specific Isopeptidases Tuning Cardiac SUMOylation in Health and Disease

SUMOylation is a transient posttranslational modification with small-ubiquitin like modifiers (SUMO1, SUMO2 and SUMO3) covalently attached to their target-proteins via a multi-step enzymatic cascade. SUMOylation modifies protein-protein interactions, enzymatic-activity or chromatin binding in a mult...

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Detalles Bibliográficos
Autores principales: Hotz, Paul W., Müller, Stefan, Mendler, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641784/
https://www.ncbi.nlm.nih.gov/pubmed/34869605
http://dx.doi.org/10.3389/fmolb.2021.786136

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