Rhinovirus-induced Human Lung Tissue Responses Mimic Chronic Obstructive Pulmonary Disease and Asthma Gene Signatures

Human rhinovirus (RV) is a major risk factor for chronic obstructive pulmonary disease (COPD) and asthma exacerbations. The exploration of RV pathogenesis has been hampered by a lack of disease-relevant model systems. We performed a detailed characterization of host responses to RV infection in huma...

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Detalles Bibliográficos
Autores principales: Wronski, Sabine, Beinke, Soren, Obernolte, Helena, Belyaev, Nikolai N., Saunders, Ken A., Lennon, Mark G., Schaudien, Dirk, Braubach, Peter, Jonigk, Danny, Warnecke, Gregor, Zardo, Patrick, Fieguth, Hans-Gerd, Wilkens, Ludwig, Braun, Armin, Hessel, Edith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641849/
https://www.ncbi.nlm.nih.gov/pubmed/34181859
http://dx.doi.org/10.1165/rcmb.2020-0337OC

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