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MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects in the Golgi apparatus lead to various diseases, but its role in organismal longevity is largely unknown. Using a quantitative proteomic approach, we found that a Golgi protein, MON-2, was up-regulat...
Autores principales: | Jung, Yoonji, Artan, Murat, Kim, Nari, Yeom, Jeonghun, Hwang, Ara B., Jeong, Dae-Eun, Altintas, Özlem, Seo, Keunhee, Seo, Mihwa, Lee, Dongyeop, Hwang, Wooseon, Lee, Yujin, Sohn, Jooyeon, Kim, Eun Ji E., Ju, Sungeun, Han, Seong Kyu, Nam, Hyun-Jun, Adams, Linnea, Ryu, Youngjae, Moon, Dong Jin, Kang, Chanhee, Yoo, Joo-Yeon, Park, Sang Ki, Ha, Chang Man, Hansen, Malene, Kim, Sanguk, Lee, Cheolju, Park, Seung-Yeol, Lee, Seung-Jae V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641931/ https://www.ncbi.nlm.nih.gov/pubmed/34860542 http://dx.doi.org/10.1126/sciadv.abj8156 |
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