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Neutrophil-mediated oxidative stress and albumin structural damage predict COVID-19-associated mortality

Human serum albumin (HSA) is the frontline antioxidant protein in blood with established anti-inflammatory and anticoagulation functions. Here, we report that COVID-19-induced oxidative stress inflicts structural damages to HSA and is linked with mortality outcome in critically ill patients. We recr...

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Detalles Bibliográficos
Autores principales: Badawy, Mohamed A, Yasseen, Basma A, El-Messiery, Riem M, Abdel-Rahman, Engy A, Elkhodiry, Aya A, Kamel, Azza G, El-sayed, Hajar, Shedra, Asmaa M, Hamdy, Rehab, Zidan, Mona, Al-Raawi, Diaa, Hammad, Mahmoud, Elsharkawy, Nahla, El Ansary, Mohamed, Al-Halfawy, Ahmed, Elhadad, Alaa, Hatem, Ashraf, Abouelnaga, Sherif, Dugan, Laura L, Ali, Sameh Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641949/
https://www.ncbi.nlm.nih.gov/pubmed/34821549
http://dx.doi.org/10.7554/eLife.69417