Cargando…

Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cells

Inflammation is associated with the development of several cancers, including breast cancer. However, the molecular mechanisms driving breast cancer initiation or enhancement by inflammation are yet to be deciphered. Hence, we opted to investigate the role of inflammation in initiating and enhancing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yassine, Farah, Fostok, Sabreen F., Al Deen, Nataly Naser, Talhouk, Rabih S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642002/ https://www.ncbi.nlm.nih.gov/pubmed/34868543 http://dx.doi.org/10.1155/2021/4666380

Ejemplares similares

Over-expression of miR-183-5p or miR-492 triggers invasion and proliferation and loss of polarity in non-neoplastic breast epithelium
por: Naser Al Deen, Nataly, et al.
Publicado: (2022)

Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling
por: Fostok, Sabreen, et al.
Publicado: (2019)

Expression of Mn-Superoxide Dismutase Gene in Nontumorigenic and Tumorigenic Human Mammary Epithelial Cells
por: Mukhopadhyay, Sutapa, et al.
Publicado: (2004)

A risk progression breast epithelial 3D culture model reveals Cx43/hsa_circ_0077755/miR-182 as a biomarker axis for heightened risk of breast cancer initiation
por: Naser Al Deen, Nataly, et al.
Publicado: (2021)

Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer
por: Naser Al Deen, Nataly, et al.
Publicado: (2019)

Inflammatory responses in epithelia: endotoxin-induced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells
por: Maalouf, Samar W, et al.
Publicado: (2010)

Short‐term exposure to ethanol induces transcriptional changes in nontumorigenic breast cells
por: Miller, Georgiana M., et al.
Publicado: (2023)

Somatotroph-Specific Aip-Deficient Mice Display Pretumorigenic Alterations in Cell-Cycle Signaling
por: Gillam, Mary P., et al.
Publicado: (2017)

Metabolomic and Mitochondrial Fingerprinting of the Epithelial-to-Mesenchymal Transition (EMT) in Non-Tumorigenic and Tumorigenic Human Breast Cells
por: Cuyàs, Elisabet, et al.
Publicado: (2022)

Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus
por: Fostok, Sabreen F, et al.
Publicado: (2009)

FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation
por: Mieczkowski, Kamil, et al.
Publicado: (2023)

Short-term exposure of nontumorigenic human bronchial epithelial cells to carcinogenic chromium(VI) compromises their respiratory capacity and alters their bioenergetic signature
por: Cerveira, Joana F., et al.
Publicado: (2014)

Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line
por: Ruiz, Graciela, et al.
Publicado: (2019)

Antiproliferation effect of imatinib mesylate on MCF7, T-47D tumorigenic and MCF 10A nontumorigenic breast cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF genes
por: Kadivar, Ali, et al.
Publicado: (2017)

Cat amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation
por: Vidane, Atanasio S, et al.
Publicado: (2014)

HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR
por: Ingthorsson, S, et al.
Publicado: (2016)

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
por: Lotz, Michael, et al.
Publicado: (2006)

Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment
por: Apostoli, Anthony J, et al.
Publicado: (2014)

“Pulsed Hypoxia” Gradually Reprograms Breast Cancer Fibroblasts into Pro-Tumorigenic Cells via Mesenchymal–Epithelial Transition
por: Nushtaeva, Anna, et al.
Publicado: (2023)

Pluripotent nontumorigenic multilineage differentiating stress enduring cells (Muse cells): a seven-year retrospective
por: Fisch, Samantha C., et al.
Publicado: (2017)

Anti-proliferative and anti-inflammatory activities of the sea cucumber Holothuria polii aqueous extract
por: Kareh, Mike, et al.
Publicado: (2018)

Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas
por: Xia, Pengpeng, et al.
Publicado: (2016)

Nucleoli in epithelial cell collectives respond to tumorigenic, spatial, and mechanical cues
por: Flick Jaecker, Florence, et al.
Publicado: (2022)

Generation of Stable Epithelial–Mesenchymal Hybrid Cancer Cells with Tumorigenic Potential
por: Tedja, Roslyn, et al.
Publicado: (2023)

Activity and expression of progesterone metabolizing 5α-reductase, 20α-hydroxysteroid oxidoreductase and 3α(β)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells
por: Wiebe, John P, et al.
Publicado: (2003)

Expression of TRPC6 channels in human epithelial breast cancer cells
por: Guilbert, Arnaud, et al.
Publicado: (2008)

Comparative proteomic data of M13SV1 human breast epithelial cells and their tumorigenic variants under treatment with estrogenic compounds
por: Braeuning, Albert, et al.
Publicado: (2016)

Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues—A Paradigm Shift in Tissue Regeneration and Evolution
por: Simerman, Ariel A., et al.
Publicado: (2016)

Pioglitazone Alters the Proteomes of Normal Bladder Epithelial Cells but Shows No Tumorigenic Effects
por: Shahid, Muhammad, et al.
Publicado: (2020)

Human Nontumorigenic Microglia Synthesize Strongly Fluorescent Au/Fe Nanoclusters, Retaining Bioavailability
por: Agans, Richard T., et al.
Publicado: (2020)

Embryonic Stem Cells Are Redirected to Non-Tumorigenic Epithelial Cell Fate by Interaction with the Mammary Microenvironment
por: Boulanger, Corinne A., et al.
Publicado: (2013)

STK31 Is a Cell-Cycle Regulated Protein That Contributes to the Tumorigenicity of Epithelial Cancer Cells
por: Kuo, Pao-Lin, et al.
Publicado: (2014)

Effects on G2/M Phase Cell Cycle Distribution and Aneuploidy Formation of Exposure to a 60 Hz Electromagnetic Field in Combination with Ionizing Radiation or Hydrogen Peroxide in L132 Nontumorigenic Human Lung Epithelial Cells
por: Jin, Hee, et al.
Publicado: (2015)

Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells
por: He, Xiaoqing, et al.
Publicado: (2017)

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
por: Grimshaw, Matthew J, et al.
Publicado: (2008)

The Role of Cancer-Derived Exosomes in Tumorigenicity & Epithelial-to-Mesenchymal Transition
por: Blackwell, Robert H., et al.
Publicado: (2017)

Increased Epithelial Oxygenation Links Colitis to an Expansion of Tumorigenic Bacteria
por: Cevallos, Stephanie A., et al.
Publicado: (2019)

Extracellular Matrix Derived from High Metastatic Human Breast Cancer Triggers Epithelial-Mesenchymal Transition in Epithelial Breast Cancer Cells through αvβ3 Integrin
por: Machado Brandão-Costa, Renata, et al.
Publicado: (2020)

Epithelial Cell-Derived Extracellular Vesicles Trigger the Differentiation of Two Epithelial Cell Lines
por: Ramos, Tiago, et al.
Publicado: (2022)

Proteomic Analysis of Blood Exosomes from Healthy Females and Breast Cancer Patients Reveals an Association between Different Exosomal Bioactivity on Non-tumorigenic Epithelial Cell and Breast Cancer Cell Migration in Vitro
por: Tutanov, Oleg, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3plr9ol5fhl6kvcp26rc76nb72