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Meta-analysis of Different Pressing Time on the Incidence of Subcutaneous Hemorrhage of Low Molecular Weight Heparin Administration
To investigate the effect of different pressing time on the incidence of subcutaneous hemorrhage of low molecular weight heparin (LMWH) administration by meta-analysis. Cochrane Library, PubMed, MEDLINE, CINAHL, EMbase, Springer, EBSCO, China Biomedical Literature Database, CNKI, Wanfang Database, a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642065/ https://www.ncbi.nlm.nih.gov/pubmed/34541913 http://dx.doi.org/10.1177/10760296211038682 |
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author | Fang, Juan Pan, Gefeng Bao, Xufei Wang, Yanhong |
author_facet | Fang, Juan Pan, Gefeng Bao, Xufei Wang, Yanhong |
author_sort | Fang, Juan |
collection | PubMed |
description | To investigate the effect of different pressing time on the incidence of subcutaneous hemorrhage of low molecular weight heparin (LMWH) administration by meta-analysis. Cochrane Library, PubMed, MEDLINE, CINAHL, EMbase, Springer, EBSCO, China Biomedical Literature Database, CNKI, Wanfang Database, and VIP Database were searched. To screen the literature of randomized controlled trials with different pressing time in patients with subcutaneous LMWH injection from the establishment of the database to December 2020. The quality of the literature was evaluated and the data were extracted. Meta-analysis was performed by RevMan 5.3. A total of 17 randomized controlled trials were included. Meta-analysis showed that the bleeding rate of pressing for 5 min odds ratio (OR = 3.89, 95% confidence interval [CI]: 2.68-5.64, P < .05) or pressing for 10 min (OR = 1.99, 95% CI: 1.34-2.95) was significantly lower than that of pressing for 3 min. Moreover, the bleeding rate was significantly lower in the 5 min pressing (OR = 1.47, 95% CI: 1.18-1.82) and 10 min pressing(OR = 2.12, 95% CI: 1.61-2.77) than in the no compression group. It is the most suitable time to press 5 min after subcutaneous LMWH injection, which can better control the incidence of bleeding. |
format | Online Article Text |
id | pubmed-8642065 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-86420652021-12-04 Meta-analysis of Different Pressing Time on the Incidence of Subcutaneous Hemorrhage of Low Molecular Weight Heparin Administration Fang, Juan Pan, Gefeng Bao, Xufei Wang, Yanhong Clin Appl Thromb Hemost Original Article To investigate the effect of different pressing time on the incidence of subcutaneous hemorrhage of low molecular weight heparin (LMWH) administration by meta-analysis. Cochrane Library, PubMed, MEDLINE, CINAHL, EMbase, Springer, EBSCO, China Biomedical Literature Database, CNKI, Wanfang Database, and VIP Database were searched. To screen the literature of randomized controlled trials with different pressing time in patients with subcutaneous LMWH injection from the establishment of the database to December 2020. The quality of the literature was evaluated and the data were extracted. Meta-analysis was performed by RevMan 5.3. A total of 17 randomized controlled trials were included. Meta-analysis showed that the bleeding rate of pressing for 5 min odds ratio (OR = 3.89, 95% confidence interval [CI]: 2.68-5.64, P < .05) or pressing for 10 min (OR = 1.99, 95% CI: 1.34-2.95) was significantly lower than that of pressing for 3 min. Moreover, the bleeding rate was significantly lower in the 5 min pressing (OR = 1.47, 95% CI: 1.18-1.82) and 10 min pressing(OR = 2.12, 95% CI: 1.61-2.77) than in the no compression group. It is the most suitable time to press 5 min after subcutaneous LMWH injection, which can better control the incidence of bleeding. SAGE Publications 2021-09-20 /pmc/articles/PMC8642065/ /pubmed/34541913 http://dx.doi.org/10.1177/10760296211038682 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Fang, Juan Pan, Gefeng Bao, Xufei Wang, Yanhong Meta-analysis of Different Pressing Time on the Incidence of Subcutaneous Hemorrhage of Low Molecular Weight Heparin Administration |
title | Meta-analysis of Different Pressing Time on the Incidence of
Subcutaneous Hemorrhage of Low Molecular Weight Heparin
Administration |
title_full | Meta-analysis of Different Pressing Time on the Incidence of
Subcutaneous Hemorrhage of Low Molecular Weight Heparin
Administration |
title_fullStr | Meta-analysis of Different Pressing Time on the Incidence of
Subcutaneous Hemorrhage of Low Molecular Weight Heparin
Administration |
title_full_unstemmed | Meta-analysis of Different Pressing Time on the Incidence of
Subcutaneous Hemorrhage of Low Molecular Weight Heparin
Administration |
title_short | Meta-analysis of Different Pressing Time on the Incidence of
Subcutaneous Hemorrhage of Low Molecular Weight Heparin
Administration |
title_sort | meta-analysis of different pressing time on the incidence of
subcutaneous hemorrhage of low molecular weight heparin
administration |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642065/ https://www.ncbi.nlm.nih.gov/pubmed/34541913 http://dx.doi.org/10.1177/10760296211038682 |
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