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Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding

The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Beta (B.1.351) and Gamma (P.1) variants of concern (VoCs) include a key mutation (N501Y) found in the Alpha (B.1.1.7) variant that enhances affinity of the spike protein for its receptor, angiotensin-converting enzyme...

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Detalles Bibliográficos
Autores principales:	Mannar, Dhiraj, Saville, James W., Zhu, Xing, Srivastava, Shanti S., Berezuk, Alison M., Zhou, Steven, Tuttle, Katharine S., Kim, Andrew, Li, Wei, Dimitrov, Dimiter S., Subramaniam, Sriram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642162/ https://www.ncbi.nlm.nih.gov/pubmed/34914928 http://dx.doi.org/10.1016/j.celrep.2021.110156

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