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Robust IgM responses following intravenous vaccination with Bacille Calmette–Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques

Development of an effective tuberculosis (TB) vaccine has suffered from an incomplete understanding of the correlates of protection against Mycobacterium tuberculosis (Mtb). Intravenous (i.v.) vaccination with Bacille Calmette–Guérin (BCG) provides nearly complete protection against TB in rhesus mac...

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Detalles Bibliográficos
Autores principales: Irvine, Edward B., O’Neil, Anthony, Darrah, Patricia A., Shin, Sally, Choudhary, Alok, Li, Wenjun, Honnen, William, Mehra, Smriti, Kaushal, Deepak, Gideon, Hannah Priyadarshini, Flynn, JoAnne L., Roederer, Mario, Seder, Robert A., Pinter, Abraham, Fortune, Sarah, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642241/
https://www.ncbi.nlm.nih.gov/pubmed/34811542
http://dx.doi.org/10.1038/s41590-021-01066-1