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CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes

Animals are essential genetic tools in scientific research and global resources in agriculture. In both arenas, a single sex is often required in surplus. The ethical and financial burden of producing and culling animals of the undesired sex is considerable. Using the mouse as a model, we develop a...

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Detalles Bibliográficos
Autores principales:	Douglas, Charlotte, Maciulyte, Valdone, Zohren, Jasmin, Snell, Daniel M., Mahadevaiah, Shantha K., Ojarikre, Obah A., Ellis, Peter J. I., Turner, James M. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642469/ https://www.ncbi.nlm.nih.gov/pubmed/34862376 http://dx.doi.org/10.1038/s41467-021-27227-2

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