Cargando…

A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a semi-supervised deep-clustering method, which examines neuroanatomical heterogeneity contrasted against normal brain str...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Zhijian, Nasrallah, Ilya M., Shou, Haochang, Wen, Junhao, Doshi, Jimit, Habes, Mohamad, Erus, Guray, Abdulkadir, Ahmed, Resnick, Susan M., Albert, Marilyn S., Maruff, Paul, Fripp, Jurgen, Morris, John C., Wolk, David A., Davatzikos, Christos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642554/ https://www.ncbi.nlm.nih.gov/pubmed/34862382 http://dx.doi.org/10.1038/s41467-021-26703-z

Ejemplares similares

Disentangling Alzheimer’s disease neurodegeneration from typical brain ageing using machine learning
por: Hwang, Gyujoon, et al.
Publicado: (2022)

Regional tract-specific white matter hyperintensities are associated with patterns of aging-related brain atrophy via vascular risk factors, but also independently
por: Habes, Mohamad, et al.
Publicado: (2018)

White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration
por: Kandel, Benjamin M., et al.
Publicado: (2016)

Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability
por: Wen, Junhao, et al.
Publicado: (2023)

Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults
por: Armstrong, Nicole M., et al.
Publicado: (2019)

Diagnostic potential of structural neuroimaging for depression from a multi-ethnic community sample
por: Sankar, Anjali, et al.
Publicado: (2016)

METABOLOMIC SIGNATURES OF BRAIN ATROPHY PATTERNS IN AGING AND ALZHEIMER'S DISEASE
por: Tian, Qu, et al.
Publicado: (2022)

Adaptive data-driven selection of sequences of biological and cognitive markers in pre-clinical diagnosis of dementia
por: Wyss, Patric, et al.
Publicado: (2023)

Neighborhood Disadvantage, Brain, and Neurocognitive Function: Relations Among Cognitively Normal Older Adults
por: Wright, Regina, et al.
Publicado: (2020)

Brain-wide genome-wide colocalization study for integrating genetics, transcriptomics and brain morphometry in Alzheimer’s disease
por: Bao, Jingxuan, et al.
Publicado: (2023)

The Genetic Architecture of Multimodal Human Brain Age
por: Wen, Junhao, et al.
Publicado: (2023)

Race, sex, and mid‐life changes in brain health: Cardia MRI substudy
por: Moonen, Justine E.F., et al.
Publicado: (2022)

Leveraging machine learning predictive biomarkers to augment the statistical power of clinical trials with baseline magnetic resonance imaging
por: Lou, Carolyn, et al.
Publicado: (2021)

Patterns of Regional Brain Atrophy and Brain Aging in Middle- and Older-Aged Adults With Type 1 Diabetes
por: Habes, Mohamad, et al.
Publicado: (2023)

Association of Brain Volumes and White Matter Injury With Race, Ethnicity, and Cardiovascular Risk Factors: The Multi‐Ethnic Study of Atherosclerosis
por: Austin, Thomas R., et al.
Publicado: (2022)

White matter microstructure, white matter lesions, and hypertension: An examination of early surrogate markers of vascular-related brain change in midlife
por: Haight, Thaddeus, et al.
Publicado: (2018)

Self- and Partner-Reported Subjective Memory Complaints: Association with Objective Cognitive Impairment and Risk of Decline
por: Zuroff, Leah, et al.
Publicado: (2022)

Advanced brain aging: relationship with epidemiologic and genetic risk factors, and overlap with Alzheimer disease atrophy patterns
por: Habes, M, et al.
Publicado: (2016)

Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial
por: Rashid, Tanweer, et al.
Publicado: (2023)

Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias
por: Jirsaraie, Robert J., et al.
Publicado: (2022)

Design and methods of the NiCK study: neurocognitive assessment and magnetic resonance imaging analysis of children and young adults with chronic kidney disease
por: Hartung, Erum A, et al.
Publicado: (2015)

Spatial Patterns of Structural Brain Changes in Type 2 Diabetic Patients and Their Longitudinal Progression With Intensive Control of Blood Glucose
por: Erus, Guray, et al.
Publicado: (2015)

Brain extraction on MRI scans in presence of diffuse glioma: Multi-institutional performance evaluation of deep learning methods and robust modality-agnostic training()
por: Thakur, Siddhesh, et al.
Publicado: (2020)

White matter integrity as a mediator between socioeconomic status and executive function
por: Shaked, Danielle, et al.
Publicado: (2022)

Two Neuroanatomical Signatures in Schizophrenia: Expression Strengths Over the First 2 Years of Treatment and Their Relationships to Neurodevelopmental Compromise and Antipsychotic Treatment
por: du Plessis, Stefan, et al.
Publicado: (2023)

Smoking mediates the relationship between SES and brain volume: The CARDIA study
por: Dougherty, Ryan J., et al.
Publicado: (2020)

Imaging-Based Biomarkers of Cognitive Performance in Older Adults Constructed via High-Dimensional Pattern Regression Applied to MRI and PET
por: Wang, Ying, et al.
Publicado: (2013)

DEEPMIR: a deep neural network for differential detection of cerebral microbleeds and iron deposits in MRI
por: Rashid, Tanweer, et al.
Publicado: (2021)

Disparities in Diffuse Cortical White Matter Integrity Between Socioeconomic Groups
por: Shaked, Danielle, et al.
Publicado: (2019)

Patent Foramen Ovale Closure Decreases the Incidence but Not the Size of New Brain Infarction on Magnetic Resonance Imaging: An Analysis of the REDUCE Trial
por: Messé, Steven R., et al.
Publicado: (2021)

Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium
por: Dwyer, Dominic B., et al.
Publicado: (2023)

Applications of generative adversarial networks in neuroimaging and clinical neuroscience
por: Wang, Rongguang, et al.
Publicado: (2023)

Neuroanatomical Classification in a Population-Based Sample of Psychotic Major Depression and Bipolar I Disorder with 1 Year of Diagnostic Stability
por: Serpa, Mauricio H., et al.
Publicado: (2014)

Vitamin D, Folate, and Cobalamin Serum Concentrations Are Related to Brain Volume and White Matter Integrity in Urban Adults
por: Beydoun, May A., et al.
Publicado: (2020)

Corrigendum: Vitamin D, Folate, and Cobalamin Serum Concentrations Are Related to Brain Volume and White Matter Integrity in Urban Adults
por: Beydoun, May A., et al.
Publicado: (2021)

An Alzheimer’s Disease-Derived Biomarker Signature Identifies Parkinson’s Disease Patients with Dementia
por: Berlyand, Yosef, et al.
Publicado: (2016)

Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study
por: Zheng, Yinan, et al.
Publicado: (2022)

Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization
por: Hu, Fengling, et al.
Publicado: (2023)

Cognitive and Neuroimaging Profiles of Individuals With Dual Decline in Memory and Gait
por: Tian, Qu, et al.
Publicado: (2020)

Multimodal Magnetic Resonance Imaging Study of Treatment-Naïve Adults with Attention-Deficit/Hyperactivity Disorder
por: Chaim, Tiffany M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_elo39umcv188hpfutub2b24e65