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Rad50 promotes ovarian cancer progression through NF‐κB activation

Rad50 is a component of MRN (Mre11‐Rad50‐Nbs1), which participates in DNA double‐strand break repair and DNA‐damage checkpoint activation. Here, we sought to investigate the clinical and functional significance of Rad50 in high‐grade serous ovarian cancer (HGSOC). We found that Rad50 was frequently...

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Detalles Bibliográficos
Autores principales: Li, Yinuo, Wang, Shourong, Li, Peng, Li, Yingwei, Liu, Yao, Fang, Haiya, Zhang, Xiyu, Liu, Zhaojian, Kong, Beihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642684/
https://www.ncbi.nlm.nih.gov/pubmed/34734468
http://dx.doi.org/10.1111/jcmm.17017