Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa

Purpose: This study aimed to design gentamicin-conjugated poly (amidoamine) (PAMAM) dendrimers to increase the therapeutic efficiency of gentamicin against Pseudomonas aeruginosa. Methods: Gentamicin-presenting dendrimers were synthesized using MAL-PEG(3400)-NHS as a redox-sensitive linker to attach...

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Detalles Bibliográficos
Autores principales: Sheykhloo, Hamed, Milani, Morteza, Najafi, Farhood, Bani, Farhad, Zarebkohan, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642794/
https://www.ncbi.nlm.nih.gov/pubmed/34888214
http://dx.doi.org/10.34172/apb.2021.076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642794/
https://www.ncbi.nlm.nih.gov/pubmed/34888214
http://dx.doi.org/10.34172/apb.2021.076

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