A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway

BACKGROUND: SATB2-associated syndrome (SAS) is a multisystem disorder caused by mutation of human SATB2 gene. Tooth agenesis is one of the most common phenotypes observed in SAS. Our study aimed at identifying novel variant of SATB2 in a patient with SAS, and to investigate the cellular and molecula...

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Detalles Bibliográficos
Autores principales: Xin, Tianyi, Li, Qian, Bai, Rushui, Zhang, Ting, Zhou, Yanheng, Zhang, Yuehua, Han, Bing, Yang, Ruili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642962/
https://www.ncbi.nlm.nih.gov/pubmed/34863303
http://dx.doi.org/10.1186/s13287-021-02660-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642962/
https://www.ncbi.nlm.nih.gov/pubmed/34863303
http://dx.doi.org/10.1186/s13287-021-02660-8

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