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A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway
BACKGROUND: SATB2-associated syndrome (SAS) is a multisystem disorder caused by mutation of human SATB2 gene. Tooth agenesis is one of the most common phenotypes observed in SAS. Our study aimed at identifying novel variant of SATB2 in a patient with SAS, and to investigate the cellular and molecula...
Autores principales: | Xin, Tianyi, Li, Qian, Bai, Rushui, Zhang, Ting, Zhou, Yanheng, Zhang, Yuehua, Han, Bing, Yang, Ruili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642962/ https://www.ncbi.nlm.nih.gov/pubmed/34863303 http://dx.doi.org/10.1186/s13287-021-02660-8 |
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