Eribulin activity in soft tissue sarcoma monolayer and three-dimensional cell line models: could the combination with other drugs improve its antitumoral effect?

BACKGROUND: Eribulin has shown antitumour activity in some soft tissue sarcomas (STSs), but it has only been approved for advanced liposarcoma (LPS). METHODS: In this study, we evaluated the effect of eribulin on proliferation, migration and invasion capabilities in LPS, leiomyosarcoma (LMS) and fib...

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Detalles Bibliográficos
Autores principales: Escudero, Javier, Heredia-Soto, Victoria, Wang, Yinyin, Ruiz, Patricia, Hu, Yingying, Gallego, Alejandro, Pozo-Kreilinger, Jose Juan, Martinez-Marin, Virginia, Berjon, Alberto, Ortiz-Cruz, Eduardo, Bernabeu, Daniel, Feliu, Jaime, Tang, Jing, Redondo, Andres, Mendiola, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642967/
https://www.ncbi.nlm.nih.gov/pubmed/34863177
http://dx.doi.org/10.1186/s12935-021-02337-5

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