ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism

BACKGROUND: Kidney cancer is a common adult malignancy in the USA. Clear cell renal cell carcinoma (ccRCC), the predominant subtype of kidney cancer, is characterized by widespread metabolic changes. Urea metabolism is one such altered pathway in ccRCC. The aim of this study was to elucidate the con...

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Detalles Bibliográficos
Autores principales: Khare, Sanika, Kim, Laura C., Lobel, Graham, Doulias, Paschalis-Thomas, Ischiropoulos, Harry, Nissim, Itzhak, Keith, Brian, Simon, M. Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642968/
https://www.ncbi.nlm.nih.gov/pubmed/34861885
http://dx.doi.org/10.1186/s40170-021-00271-8

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