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Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment

BACKGROUND: High glucose (HG) is linked to dopaminergic neuron loss and related Parkinson’s disease (PD), but the mechanism is unclear. RESULTS: Rats and differentiated SH-SY5Y cells were used to investigate the effect of HG on dopaminergic neuronal apoptotic death. We found that a 40-day HG diet el...

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Detalles Bibliográficos
Autores principales: Tan, Changhong, Liu, Xi, Zhang, Xiaoshuai, Peng, Wuxue, Wang, Hui, Zhou, Wen, Jiang, Jin, Mo, Lijuan, Chen, Yangmei, Chen, Lifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642997/
https://www.ncbi.nlm.nih.gov/pubmed/34863087
http://dx.doi.org/10.1186/s12860-021-00398-y

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