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MiRNA-221-5p suppressed the Th17/Treg ratio in asthma via RORγt/Foxp3 by targeting SOCS1

BACKGROUND: This study was designed to investigate the mechanism and effects of miRNA-221-5p on the T-helper 17 (Th17)/T-regulatory (Treg) ratio in asthma. METHODS: BALB/c mice were intranasally challenged with 100 µg OVA on 14 and 21 day. Mice were rechallenged with 2.5% OVA-PBS on 22 and 28 day. M...

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Detalles Bibliográficos
Autores principales:	Guan, Yuanyuan, Ma, Yuemei, Tang, Yao, Liu, Xiaolei, Zhao, Yan, An, Lixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643019/ https://www.ncbi.nlm.nih.gov/pubmed/34863307 http://dx.doi.org/10.1186/s13223-021-00620-8

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