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Effects of adenovirus-mediated knockdown of IRAK4 on synovitis in the osteoarthritis rabbit model

BACKGROUND: The use of interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor as a treatment for the inflammatory joint disease is a promising method. However, its underlying mechanism in osteoarthritis (OA) remains unclear. The purpose of this study is to look into the effects of adenovirus-m...

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Detalles Bibliográficos
Autores principales: Li, Muzhe, Li, Huiyun, Ran, Xun, Yin, Han, Luo, Xuling, Chen, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643028/
https://www.ncbi.nlm.nih.gov/pubmed/34863246
http://dx.doi.org/10.1186/s13075-021-02684-8