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Methylcobalamin Protects Melanocytes from H(2)O(2)-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway

PURPOSE: Oxidative stress is considered a major determinant in the pathogenesis of vitiligo. Methylcobalamin (MeCbl) is an activated form of vitamin B12 that regulates inflammatory factors, counters oxidative stress, and reduces apoptosis in many disease models. However, the specific mechanism of Me...

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Detalles Bibliográficos
Autores principales: An, Ran, Li, Dong, Dong, Yingying, She, Qiuyun, Zhou, Ting, Nie, Xiaoqi, Pan, Ronghua, Deng, Yunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643160/
https://www.ncbi.nlm.nih.gov/pubmed/34876806
http://dx.doi.org/10.2147/DDDT.S336066