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Assessment to the Antifungal Effects in vitro and the Ocular Pharmacokinetics of Solid-Lipid Nanoparticle in Rabbits

INTRODUCTION: Fungal keratitis (FK) remains a severe sight-threatening disease, and case management is difficult due to ocular intrinsic barriers and drug shortages. Econazole (ECZ), a broad-spectrum antifungal agent, is limited in ocular applications due to the poor water solubility and strong irri...

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Detalles Bibliográficos
Autores principales: Liang, Zhen, Zhang, Zhen, Yang, Jingjing, Lu, Ping, Zhou, Tianyang, Li, Jingguo, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643199/
https://www.ncbi.nlm.nih.gov/pubmed/34876813
http://dx.doi.org/10.2147/IJN.S340068