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Assessment to the Antifungal Effects in vitro and the Ocular Pharmacokinetics of Solid-Lipid Nanoparticle in Rabbits
INTRODUCTION: Fungal keratitis (FK) remains a severe sight-threatening disease, and case management is difficult due to ocular intrinsic barriers and drug shortages. Econazole (ECZ), a broad-spectrum antifungal agent, is limited in ocular applications due to the poor water solubility and strong irri...
Autores principales: | Liang, Zhen, Zhang, Zhen, Yang, Jingjing, Lu, Ping, Zhou, Tianyang, Li, Jingguo, Zhang, Junjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643199/ https://www.ncbi.nlm.nih.gov/pubmed/34876813 http://dx.doi.org/10.2147/IJN.S340068 |
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