Cargando…
ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish
Mechanistic target of rapamycin (mTOR) signaling governs important physiological and pathological processes key to cellular life. Loss of mTOR negative regulators and subsequent over-activation of mTOR signaling are major causes underlying epileptic encephalopathy. Our previous studies showed that U...
Autores principales: | Wang, Tiantian, Zhou, Mingshan, Zhang, Quan, Zhang, Cuizhen, Peng, Gang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643380/ https://www.ncbi.nlm.nih.gov/pubmed/34309811 http://dx.doi.org/10.1007/s12264-021-00755-z |
Ejemplares similares
-
UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling
por: Zhang, Hefei, et al.
Publicado: (2018) -
Depdc5 knockdown causes mTOR‐dependent motor hyperactivity in zebrafish
por: de Calbiac, Hortense, et al.
Publicado: (2018) -
Overcoming mTOR Resistance Mutations with a New Generation mTOR Inhibitor
por: Rodrik-Outmezguine, Vanessa S., et al.
Publicado: (2016) -
Commentary: Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
por: Renna, Maurizio
Publicado: (2016) -
RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity
por: Proietti Onori, Martina, et al.
Publicado: (2021)