Spatial concordance of DNA methylation classification in diffuse glioma

BACKGROUND: Intratumoral heterogeneity is a hallmark of diffuse gliomas. DNA methylation profiling is an emerging approach in the clinical classification of brain tumors. The goal of this study is to investigate the effects of intratumoral heterogeneity on classification confidence. METHODS: We used...

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Detalles Bibliográficos
Autores principales: Verburg, Niels, Barthel, Floris P, Anderson, Kevin J, Johnson, Kevin C, Koopman, Thomas, Yaqub, Maqsood M, Hoekstra, Otto S, Lammertsma, Adriaan A, Barkhof, Frederik, Pouwels, Petra J W, Reijneveld, Jaap C, Rozemuller, Annemieke J M, Beliën, Jeroen A M, Boellaard, Ronald, Taylor, Michael D, Das, Sunit, Costello, Joseph F, Vandertop, William Peter, Wesseling, Pieter, de Witt Hamer, Philip C, Verhaak, Roel G W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643482/
https://www.ncbi.nlm.nih.gov/pubmed/34049406
http://dx.doi.org/10.1093/neuonc/noab134

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