Effective therapeutic strategies in a preclinical mouse model of Charcot–Marie–Tooth disease

Charcot–Marie–Tooth (CMT) disease is a neuropathy that lacks effective therapy. CMT patients show degeneration of peripheral nerves, leading to muscle weakness and loss of proprioception. Loss of mitochondrial oxidative phosphorylation proteins and enzymes of the antioxidant response accompany degen...

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Detalles Bibliográficos
Autores principales: Nuevo-Tapioles, Cristina, Santacatterina, Fulvio, Sánchez-Garrido, Brenda, de Arenas, Cristina Núñez, Robledo-Bérgamo, Adrián, Martínez-Valero, Paula, Cantarero, Lara, Pardo, Beatriz, Hoenicka, Janet, Murphy, Michael P, Satrústegui, Jorgina, Palau, Francesc, Cuezva, José M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643506/
https://www.ncbi.nlm.nih.gov/pubmed/34274972
http://dx.doi.org/10.1093/hmg/ddab207

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