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BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity

Subunits of the chromatin remodeler SWI/SNF are the most frequently disrupted genes in cancer. However, how post-translational modifications (PTM) of SWI/SNF subunits elicit epigenetic dysfunction remains unknown. Arginine-methylation of BAF155 by coactivator-associated arginine methyltransferase 1...

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Detalles Bibliográficos
Autores principales: Kim, Eui-Jun, Liu, Peng, Zhang, Shengjie, Donahue, Kristine, Wang, Yidan, Schehr, Jennifer L, Wolfe, Serena K, Dickerson, Amber, Lu, Li, Rui, Lixin, Zhong, Xuehua, Wisinski, Kari B, Yu, Min, Suzuki, Aussie, Lang, Joshua M, Ong, Irene M, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643633/
https://www.ncbi.nlm.nih.gov/pubmed/34865122
http://dx.doi.org/10.1093/nar/gkab1122