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Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry

DNA replication is a key step in initiating cell proliferation. Loading hexameric complexes of minichromosome maintenance (MCM) helicase onto DNA replication origins during the G1 phase is essential for initiating DNA replication. Here, we examined MCM hexamer states during the cell cycle in human h...

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Detalles Bibliográficos
Autores principales: Hayashi-Takanaka, Yoko, Hayashi, Yuichiro, Hirano, Yasuhiro, Miyawaki-Kuwakado, Atsuko, Ohkawa, Yasuyuki, Obuse, Chikashi, Kimura, Hiroshi, Haraguchi, Tokuko, Hiraoka, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643670/
https://www.ncbi.nlm.nih.gov/pubmed/34817054
http://dx.doi.org/10.1093/nar/gkab1068