Cargando…
Cellular heterogeneity in DNA alkylation repair increases population genetic plasticity
DNA repair mechanisms fulfil a dual role, as they are essential for cell survival and genome maintenance. Here, we studied how cells regulate the interplay between DNA repair and mutation. We focused on the adaptive response that increases the resistance of Escherichia coli cells to DNA alkylation d...
Autores principales: | Vincent, Maxence S, Uphoff, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643705/ https://www.ncbi.nlm.nih.gov/pubmed/34850170 http://dx.doi.org/10.1093/nar/gkab1143 |
Ejemplares similares
-
Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein
por: Perugino, Giuseppe, et al.
Publicado: (2015) -
Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase
por: Mohan, Monisha, et al.
Publicado: (2019) -
Architectural plasticity of human BRCA2–RAD51 complexes in DNA break repair
por: Sánchez, Humberto, et al.
Publicado: (2017) -
The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products
por: Godin, Stephen K., et al.
Publicado: (2016) -
DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)