112. A Rapid Host-Protein Signature Based on TNF-related Apoptosis-Induced Ligand (TRAIL), Interferon Gamma Induced Protein-10 (IP-10) and C-Reactive Protein (CRP) Accurately Differentiates Between Bacterial and Viral Infection in Febrile Children: Apollo Sub-Study

BACKGROUND: Identifying infectious etiology is essential for appropriate patient management, including antibiotic use. A host-protein signature for differentiating bacterial from viral infection has exhibited robust performance (AUC of 0.9, 95% CI 0.86-0.95) in prior studies. Performance data was la...

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Detalles Bibliográficos
Autores principales: Kaplan, Sheldon L, Klein, Adi, Kellogg, Mark, Cruz, Andrea T, Hulten, Kristina G, Arias, Cesar A, Gordon, Richard, Motov, Sergey, Jacob, Theresa, Ballard, Natasha, Suits, George, Harris, Jeffrey, Shapira, Maanit, Rothman, Richard E, Carroll, Karen C, Ryan, Leticia M, Bachur, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Oral Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8643980/
http://dx.doi.org/10.1093/ofid/ofab466.112

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