1411. Noninvasive Assessment of Intralesional Antimicrobial Concentration-Time Profiles in Pulmonary and Central Nervous System Tuberculosis using Dynamic (18)F-Pretomanid Positron Emission Tomography

BACKGROUND: Pretomanid is used in combination with bedaquiline and linezolid (BPaL regimen) in the treatment of multidrug-resistant tuberculosis (MDR-TB). However, the penetration of pretomanid in privileged sites remain unknown. Antimicrobial pharmacokinetic (PK) parameters are traditionally derive...

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Detalles Bibliográficos
Autores principales: Mota, Filipa, Ruiz-Bedoya, Camilo, Tucker, Elizabeth, De Jesus, Patricia, Flavahan, Kelly, Turner, Mitchell, Erice, Clara, Bahr, Melissa, Kim, John, Mahmud, Farina, Peloquin, Charles A, Ordonez, Alvaro A, Jain, Sanjay K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644115/
http://dx.doi.org/10.1093/ofid/ofab466.1603

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