Cargando…
119. A Humanized Antibody Targeting the CotH Invasins is Protective Against Murine Mucormycosis
BACKGROUND: Despite antifungal therapy and surgical debridement, overall mortality of invasive mucormycosis is >40%. Currently the world is witnessing an explosion in mucormycosis in India among COVID-19 patients with an official count of 28,252 cases as of 06/07/2021. Thus, novel therapeutic mod...
Autores principales: | Gu, Yiyou, Alqarihi, Abdullah, Singh, Shakti, Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Youssef, Eman, Andes, David, Ibrahim, Ashraf S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644226/ http://dx.doi.org/10.1093/ofid/ofab466.119 |
Ejemplares similares
-
Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2019) -
Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2019) -
cotH Genes Are Necessary for Normal Spore Formation and Virulence in Mucor lusitanicus
por: Szebenyi, Csilla, et al.
Publicado: (2023) -
APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2019) -
969. GRP78 and Integrin β1/α3 Play Disparate Roles in Epithelium Invasion During Mucormycosis
por: Alqarihi, Abdullah, et al.
Publicado: (2018)