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1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia

BACKGROUND: IDSA/ATS guidelines regarding pneumonia diagnosis and treatment changed in 2019. Guidelines recommend determining local prevalence of MRSA and P. aeruginosa to help guide empiric antibiotic coverage. The aim of our study was to determine the prevalence of P. aeruginosa as the causative o...

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Autores principales: Haviland, Adam D, Szymczak, Wendy, Weston, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644294/
http://dx.doi.org/10.1093/ofid/ofab466.1509
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author Haviland, Adam D
Szymczak, Wendy
Weston, Gregory
author_facet Haviland, Adam D
Szymczak, Wendy
Weston, Gregory
author_sort Haviland, Adam D
collection PubMed
description BACKGROUND: IDSA/ATS guidelines regarding pneumonia diagnosis and treatment changed in 2019. Guidelines recommend determining local prevalence of MRSA and P. aeruginosa to help guide empiric antibiotic coverage. The aim of our study was to determine the prevalence of P. aeruginosa as the causative organism for adult patients admitted to a large urban academic medical center with community acquired pneumonia (CAP). METHODS: A report of urine streptococcus antigen tests collected January 1st-December 31st in 2019 was generated. Six hundred charts were reviewed and two hundred subjects met inclusion criteria (figure 1). Inclusion criteria were age >18, hospital admission, and documented suspicion of pneumonia by a physician. RESULTS: The average age was 70 and half of the cases were women. The causative organism was identified in 60/200 cases (table 1). No cases of P. aeruginosa were identified. The most commonly isolated organisms were Influenza A and pneumococcus. 66% of cases had age >65yo, 25% were from long term care facilities, 34% had structural lung disease, 20% had dementia, 15% were hospitalized in the prior 90 days and received IV antibiotics, and 30% of cases met severe CAP criteria (table 2). [Image: see text] Figure 1. Workflow Table 1. Organisms Identified [Image: see text] Table 2. Risk Factors [Image: see text] CONCLUSION: Limitations include a low prevalence of renal failure in the study population, and lack of a standardized respiratory infection evaluation. Our results suggest that empiric coverage for P. aeruginosa may not be needed at our center in this cohort of older patients with clinical characteristics sometimes thought to be risk factors for P. aeruginosa. DISCLOSURES: Wendy Szymczak, PhD, Premier, Inc (Consultant)Qiagen (Consultant, Scientific Research Study Investigator) Gregory Weston, MD MSCR, Allergan (Grant/Research Support)
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spelling pubmed-86442942021-12-06 1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia Haviland, Adam D Szymczak, Wendy Weston, Gregory Open Forum Infect Dis Poster Abstracts BACKGROUND: IDSA/ATS guidelines regarding pneumonia diagnosis and treatment changed in 2019. Guidelines recommend determining local prevalence of MRSA and P. aeruginosa to help guide empiric antibiotic coverage. The aim of our study was to determine the prevalence of P. aeruginosa as the causative organism for adult patients admitted to a large urban academic medical center with community acquired pneumonia (CAP). METHODS: A report of urine streptococcus antigen tests collected January 1st-December 31st in 2019 was generated. Six hundred charts were reviewed and two hundred subjects met inclusion criteria (figure 1). Inclusion criteria were age >18, hospital admission, and documented suspicion of pneumonia by a physician. RESULTS: The average age was 70 and half of the cases were women. The causative organism was identified in 60/200 cases (table 1). No cases of P. aeruginosa were identified. The most commonly isolated organisms were Influenza A and pneumococcus. 66% of cases had age >65yo, 25% were from long term care facilities, 34% had structural lung disease, 20% had dementia, 15% were hospitalized in the prior 90 days and received IV antibiotics, and 30% of cases met severe CAP criteria (table 2). [Image: see text] Figure 1. Workflow Table 1. Organisms Identified [Image: see text] Table 2. Risk Factors [Image: see text] CONCLUSION: Limitations include a low prevalence of renal failure in the study population, and lack of a standardized respiratory infection evaluation. Our results suggest that empiric coverage for P. aeruginosa may not be needed at our center in this cohort of older patients with clinical characteristics sometimes thought to be risk factors for P. aeruginosa. DISCLOSURES: Wendy Szymczak, PhD, Premier, Inc (Consultant)Qiagen (Consultant, Scientific Research Study Investigator) Gregory Weston, MD MSCR, Allergan (Grant/Research Support) Oxford University Press 2021-12-04 /pmc/articles/PMC8644294/ http://dx.doi.org/10.1093/ofid/ofab466.1509 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Poster Abstracts
Haviland, Adam D
Szymczak, Wendy
Weston, Gregory
1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia
title 1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia
title_full 1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia
title_fullStr 1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia
title_full_unstemmed 1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia
title_short 1317. Prevalence of Pseudomonas aeruginosa as the Causative Organism for Community Acquired Pneumonia
title_sort 1317. prevalence of pseudomonas aeruginosa as the causative organism for community acquired pneumonia
topic Poster Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644294/
http://dx.doi.org/10.1093/ofid/ofab466.1509
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