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132. Evaluation Phage Cocktails in Combination with Ciprofloxacin Against Multidrug-Resistant Pseudomonas aeruginosa Overexpressing MexAB-OprM Efflux Systems

BACKGROUND: Multidrug-resistant (MDR) Pseudomonas aeruginosa infections are increasing in prevalence and cause significant mortality. The MexAB-OprM efflux system confers resistance to a wide range of drugs, including β-lactams, fluoroquinolones, tetracyclines, and macrolides. Obligately lytic bacte...

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Detalles Bibliográficos
Autores principales: Holger, Dana, Lev, Katherine, Bhutani, Natasha, Kebriaei, Razieh, Morrisette, Taylor, Lehman, Susan, Alexander, Jose, Rybak, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644304/
http://dx.doi.org/10.1093/ofid/ofab466.132

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