Cargando…

37. Allogeneic, Off-the-Shelf, SARS-CoV-2-specific T Cells Demonstrate Reactivity Against Emerging Variant Strains

BACKGROUND: The impact of COVID-19 has been profound with >170,000,000 confirmed cases worldwide and emerging variants being a cause of global concern. Defects in T-cell function and trafficking have been described among those with severe illness, and immunodeficiency is a risk factor for persist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vasileiou, Spyridoula, Kuvalekar, Manik, Workineh, Aster, Watanabe, Ayumi, Velazquez, Yovana, Lulla, Suhasini, Heslop, Helen Elisabeth, Mooney, Kimberly, Grimes, Kevin, Carrum, George, Hill, LaQuisa, Lulla, Premal, Leen, Ann Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Oral Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644382/ http://dx.doi.org/10.1093/ofid/ofab466.037

Ejemplares similares

Allogeneic, Off-the-Shelf, Sars-Cov-2-Specific T Cells to Treat High-Risk Patients with COVID-19
por: Vasileiou, Spyridoula, et al.
Publicado: (2021)

Using Allogeneic, Off-the-Shelf, Sars-Cov-2-Specific T Cells to Treat High Risk Patients with COVID-19
por: Vasileiou, Spyridoula, et al.
Publicado: (2020)

Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients
por: Vasileiou, Spyridoula, et al.
Publicado: (2022)

COVID-specific T's may offset therapeutically endangered B's
por: Hill, LaQuisa C., et al.
Publicado: (2022)

Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination
por: Vasileiou, Spyridoula, et al.
Publicado: (2022)

Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer
por: Hoyos, Valentina, et al.
Publicado: (2022)

Rapid generation of multivirus-specific T lymphocytes for the prevention and treatment of respiratory viral infections
por: Vasileiou, Spyridoula, et al.
Publicado: (2020)

Banking on virus-specific T cells to fulfill the need for off-the-shelf cell therapies
por: Quach, David H., et al.
Publicado: (2023)

Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting
por: Pfeiffer, Thomas, et al.
Publicado: (2023)

Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs
por: Steffin, David H. M., et al.
Publicado: (2022)

Correction: Effect of Immune Reconstitution on the Incidence of HIV-Related Hodgkin Lymphoma
por: Kowalkowski, Marc A., et al.
Publicado: (2013)

Effect of Immune Reconstitution on the Incidence of HIV-Related Hodgkin Lymphoma
por: Kowalkowski, Marc A., et al.
Publicado: (2013)

CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation
por: Bajgain, Pradip, et al.
Publicado: (2018)

Expanding CAR T cells in human platelet lysate renders T cells with in vivo longevity
por: Torres Chavez, Alejandro, et al.
Publicado: (2019)

Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes
por: Lulla, Valeria, et al.
Publicado: (2016)

Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells
por: Juillerat, Alexandre, et al.
Publicado: (2020)

Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus
por: Tamberg, Nele, et al.
Publicado: (2007)

Apparent Pacer Spikes in a Patient with Back and Chest Pain
por: Lulla, Al, et al.
Publicado: (2019)

Contributions of modelling for the control of COVID-19 nosocomial transmission
por: Opatowski, Lulla, et al.
Publicado: (2022)

Immunologic Profiling of Human Metapneumovirus for the Development of Targeted Immunotherapy
por: Tzannou, Ifigeneia, et al.
Publicado: (2017)

A hidden gene in astroviruses encodes a viroporin
por: Lulla, Valeria, et al.
Publicado: (2020)

Predicting COVID-19 community infection relative risk with a Dynamic Bayesian Network
por: Johnson, Daniel P., et al.
Publicado: (2022)

Allogeneic transplant and CAR-T therapy after autologous transplant failure in DLBCL: a noncomparative cohort analysis
por: Hamadani, Mehdi, et al.
Publicado: (2022)

Allogeneic endometrial regenerative cells: An "Off the shelf solution" for critical limb ischemia?
por: Murphy, Michael P, et al.
Publicado: (2008)

Clinical Evaluation of an Off-the-Shelf Allogeneic Adipose Matrix for Soft Tissue Reconstruction
por: Kokai, Lauren E., et al.
Publicado: (2020)

Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic
por: Zhang, Xuqing, et al.
Publicado: (2021)

OTHR-02. Engineered “of the shelf” allogeneic cellular therapies for metastatic brain tumors
por: Shah, Khalid, et al.
Publicado: (2021)

Current Perspectives on “Off-The-Shelf” Allogeneic NK and CAR-NK Cell Therapies
por: Heipertz, Erica L., et al.
Publicado: (2021)

COVID-19 containment measures and incidence of invasive bacterial disease
por: Smith, David R M, et al.
Publicado: (2021)

Defining genomic epidemiology thresholds for common-source bacterial outbreaks: a modelling study
por: Duval, Audrey, et al.
Publicado: (2023)

The Importance of HLA Assessment in “Off-the-Shelf” Allogeneic Mesenchymal Stem Cells Based-Therapies
por: Kot, Marta, et al.
Publicado: (2019)

Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
por: Li, Yan-Ruide, et al.
Publicado: (2021)

CD3 engagement as a new strategy for allogeneic “off-the-shelf” T cell therapy
por: Li, Gongbo, et al.
Publicado: (2022)

Influenza interaction with cocirculating pathogens and its impact on surveillance, pathogenesis, and epidemic profile: A key role for mathematical modelling
por: Opatowski, Lulla, et al.
Publicado: (2018)

Microbiome-pathogen interactions drive epidemiological dynamics of antibiotic resistance: A modeling study applied to nosocomial pathogen control
por: Smith, David RM, et al.
Publicado: (2021)

Assessment and reporting of quality-of-life measures in pivotal clinical trials of hematological malignancies
por: Al Hadidi, Samer, et al.
Publicado: (2021)

The Mitochondrial Protease LonP1 Promotes Proteasome Inhibitor Resistance in Multiple Myeloma
por: Maneix, Laure, et al.
Publicado: (2021)

Mutations in chromatin machinery and pediatric high-grade glioma
por: Lulla, Rishi R., et al.
Publicado: (2016)

Role of Ultrasound in the Identification of Longitudinal Axis in Soft-Tissue Foreign Body Extraction
por: Lulla, Al, et al.
Publicado: (2016)

Risk assessment for antibiotic resistance in South East Asia
por: Chereau, Fanny, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ekcqd6247s1mni1f2u660coae6